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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NFE2 All Species: 23.03
Human Site: Y180 Identified Species: 56.3
UniProt: Q16621 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16621 NP_001129495.1 373 41473 Y180 V E M Y P V E Y P Y S L M P N
Chimpanzee Pan troglodytes XP_001170837 373 41424 Y180 V E M Y P V E Y P Y S L M P N
Rhesus Macaque Macaca mulatta XP_001109451 373 41470 Y180 V E M Y P V E Y P Y S L M P N
Dog Lupus familis XP_543621 373 41136 Y180 V E M Y P V E Y P Y S L M P N
Cat Felis silvestris
Mouse Mus musculus Q07279 373 41546 Y180 V D M Y P V E Y P Y S L M P N
Rat Rattus norvegicus Q6AYT2 373 41477 Y180 V D M Y P V E Y P Y S L M P N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514024 136 15506
Chicken Gallus gallus Q5ZL67 772 85168 L568 Q L H Y L P Y L E H V G H N H
Frog Xenopus laevis NP_001088660 343 38204 Q168 E L E N I E S Q R L Q V E Y M
Zebra Danio Brachydanio rerio NP_878309 586 65869 S392 D G S Q T P L S E K S S T E K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 97.8 92.2 N.A. 89 90 N.A. 28.9 24.2 32.4 30.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.7 98.6 94 N.A. 91.9 92.4 N.A. 31.8 34.5 49 43.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 0 6.6 0 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 0 20 6.6 6.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 20 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 10 40 10 0 0 10 60 0 20 0 0 0 10 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 0 0 0 0 0 0 0 0 10 0 0 0 % G
% His: 0 0 10 0 0 0 0 0 0 10 0 0 10 0 10 % H
% Ile: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 10 % K
% Leu: 0 20 0 0 10 0 10 10 0 10 0 60 0 0 0 % L
% Met: 0 0 60 0 0 0 0 0 0 0 0 0 60 0 10 % M
% Asn: 0 0 0 10 0 0 0 0 0 0 0 0 0 10 60 % N
% Pro: 0 0 0 0 60 20 0 0 60 0 0 0 0 60 0 % P
% Gln: 10 0 0 10 0 0 0 10 0 0 10 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % R
% Ser: 0 0 10 0 0 0 10 10 0 0 70 10 0 0 0 % S
% Thr: 0 0 0 0 10 0 0 0 0 0 0 0 10 0 0 % T
% Val: 60 0 0 0 0 60 0 0 0 0 10 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 70 0 0 10 60 0 60 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _